There are ample Biblical passages to support this, and all of Christian doctrine rests on the idea that there was no death, pain, and suffering before sin entered into the world (Genesis 1:31, Genesis 3:17-19, Romans 8:20-23, Romans 5:12-21, Romans 6:23...)
I've been told by some compromising Christians that death is not really a bad thing, and that it is just a natural part of life. Scripture obviously refutes this idea in I Corinthians 15:12-28 and Romans 6:23.
But after reading Matthew 13:24-30, I think (in addition to the fact that mankind brought sin,pain, death into the world) another reason why we face pain and persecution is that we have an enemy that hates us.
Here is another story Jesus told: “The Kingdom of Heaven is like a farmer who planted good seed in his field. But that night as the workers slept, his enemy came and planted weeds among the wheat, then slipped away. When the crop began to grow and produce grain, the weeds also grew. “The farmer’s workers went to him and said, ‘Sir, the field where you planted that good seed is full of weeds! Where did they come from?’ “‘An enemy has done this!’ the farmer exclaimed.The enemy of God hates Christians as well as the Creator, and as long as we are still awaiting our adoption as sons (Romans 8), we will be subject to Satan's attacks. Although unwanted and hurtful, God can use Satan's painful attacks to galvanize our faith.
So, when you feel pain and weariness, take heart that you are growing (James 1:2-4) and that followers of Christ will be ultimately victorious!